Franchise system

Prime IV Hydration & Wellness

IV hydration and nutrient infusion clinics; the brand's own line is "Look Better, Feel Better, Perform Better with Prime IV" (primeivhydration.com/about, retrieved 2026-08-10).

IV hydration and nutrient infusion (custom drips)Micronutrient / vitamin injections (B-12, Lipo-Lean)NAD+ infusions and injectionsNiagen (NAD+ precursor)Buccal nutrient stripsMedical-grade oxygen

112

verified locations (Praxium)

208

units claimed by brand (2025)

states

2017

founded

Signature offer

What makes Prime IV Hydration & Wellness different

A single-modality IV drip clinic rather than a multi-modality recovery studio — the box is small, the staffing model is thin (the brand's franchise site says as few as two medical staff run a location; Entrepreneur's 2026 listing puts the minimum at four employees), and there is no cold plunge, sauna, or cryo equipment load in the standard build. Recurring revenue comes from three membership tiers priced in drip-and-injection credits that roll over month to month, not from unlimited access. That combination produces unusually high revenue density for the footprint: the brand reports a top-performing location at $3.2M in annual revenue and $100M+ systemwide revenue for 2025 (brand press release, 2026-02-09), against a 2025 FDD Item 19 average of $567,075 for units open 12+ months in 2024.

Prime IV Hydration & Wellness is a franchised chain of small-format IV nutrient infusion clinics. Each location sells custom IV drips, micronutrient and NAD+ injections, and medical-grade oxygen from a spa-style room of massage chairs, with medical weight loss and bioidentical hormone replacement offered at select units. Revenue is built around a three-tier monthly membership in which unused drip and injection credits roll over. The system is founder-led and franchisor-operated: per the 2025 FDD Item 20 summary, 152 of 154 outlets were franchised and 2 were company-owned.

Footprint

Two counts, side by side

The brand's own unit count and Praxium's verified-location count measure different things and are shown unreconciled.

112

verified locations

Praxium’s own count — locations we linked to this brand, one by one.

208

units claimed by the brand · as of 2025

2025-12-31 — Brand press release "Prime IV Hydration & Wellness Caps Off a Landmark Year of Growth and Innovation in 2025," published 2026-02-09 (https://finance.yahoo.com/news/prime-iv-hydration-wellness-caps-151200889.html): 53 locations opened in 2025, closing the year with 208 operating locations, 324 total locations sold, across 42 states and DC. Corroborating datapoints at other dates: 189 active locations in 40 states as of 2025-12-17 (Lafayette Square press release); 215 units per Entrepreneur's 2026 Franchise 500 directory listing; 154 outlets (152 franchised / 2 company-owned) per the 2025 FDD Item 20 summary reflecting FY2024 year-end (franchisepayback.com). Praxium currently lists 112, which is a floor.

Franchise availability Open — per the brand's own materials. A status, not an endorsement.

Training is 24.5 hours classroom plus 16 hours on-the-job; minimum 4 employees; absentee ownership is not permitted; the business cannot be run from home or part-time (Entrepreneur 2026 Franchise 500 directory listing). The 2025 FDD Item 7 build-out line items include leasehold improvements of $23,000–$320,000, medical equipment and supplies of $15,000–$60,000, three months of staff salaries at $9,000–$23,400, pre-opening marketing of $19,500–$24,000, and three months of additional funds at $15,000 (FranchisePayback summary of the 2025 FDD) — the wide leasehold range is the main driver of the $190K-to-$632K spread. No brand-published or FDD-sourced buildout timeline was found.

United States only. The brand states 42 states plus the District of Columbia as of 2025-12-31 (brand press release, 2026-02-09). Entrepreneur's 2026 Franchise 500 directory listing shows franchise availability across all US states and territories and lists no Canadian or international units. No non-US locations found.

For members

What Prime IV Hydration & Wellness sells members

Three credit-based monthly tiers (primeivhydration.com/membership, retrieved 2026-08-10). SELECT: 1 primary IV drip of choice plus 1 B-12 or Lipo-Lean injection. ESSENTIALS: any 1 IV drip plus 2 injections, plus 15% off additional drips and injections. TRANSFORMATION: any 2 IV drips plus 3 injections, plus 20% off additional treatments. All tiers include VIP massage chair access, oxygen at select locations, and 50% off IV additives. Unused monthly credits automatically roll over to the following month. Tier prices are not published nationally and vary by location.

No national membership price is published. The published first-visit intro offer is $85 (regularly $144) for one primary IV infusion, a free consultation, and a massage chair or medical-grade oxygen session — observed on the Leander, TX (primeivhydration.com/locations/texas/leander-78641/) and Mason, OH location pages, verified 2026-08-08 via the Praxium corpus, and on the Colorado Springs, CO Briargate Village page. This is a trial price, not a membership rate.

On the record

Prime IV Hydration & Wellness in the news

2026-02-09
Reported 2025 results: 53 locations opened, closing the year at 208 operating locations; 35 new franchise agreements awarded bringing total sold to 324 across 42 states and DC; systemwide revenue up 41% year over year to $100M+; top-performing location at $3.2M annual revenue. Launched buccal nutrient strips, BHRT, and Niagen; entered Connecticut and Nebraska.
Source: Prime IV Hydration & Wellness press release, "Caps Off a Landmark Year of Growth and Innovation in 2025" (
2025-12-17
Received senior secured financing from Lafayette Square through its SSBIC investment vehicle to support franchise-system expansion; Boxwood Partners served as exclusive financial advisor. Amount undisclosed. Prime IV cited at 189 active locations across 40 states and described as a woman-owned business founded by Amy Neary. This is debt financing, not a sale — no change of control.
Source: Lafayette Square press release (
2026-02-09
Ranked #234 on Entrepreneur's Franchise 500 for 2026 and #1 in the IV Therapy category for the third consecutive year; ranked #597 on the 2025 Inc. 5000; Franchise Business Review #6 Top 50 Midsize Franchises and #2 in Health & Personal Services.
Source: Prime IV Hydration & Wellness press release (third-party rankings as reported by the brand); Entrepreneur Franchise 500 directory listing (
2026
FDD filings on record for 2020 through 2026, confirming continuous franchise registration since 2020 and an active current-year filing.
Source: FranchiseGenius FDD index (

Brand details

Company

Founded: 2017
Headquarters: Colorado Springs, CO
Founders: Amy Neary
Parent company: None identified. Private, founder-led franchisor; described as a woman-owned business founded by Amy Neary in the Lafayette Square financing announcement (2025-12-17). No parent holding company or PE sponsor found.

System

Ownership model: Franchise system

Franchisee support, as published

Site selection
Lease negotiation
Classroom training — 24.5 hours (Entrepreneur 2026 Franchise 500 listing)
On-the-job training — 16 hours (Entrepreneur 2026 Franchise 500 listing)
Field operations support
Proprietary software and franchisee intranet
Co-op advertising
Social media, SEO, and website development
Loyalty program
Ongoing operations team access — the brand's franchise site states "You get a team of experts available for training and help"

Visit Prime IV Hydration & Wellness ↗The brand’s franchise page ↗

The dossier

What it costs to open a Prime IV Hydration & Wellness

Terms tied to the 2025 disclosure cycle. Citations stay inline wherever the research recorded one.

Franchise fee: $49,000 per location; $39,000 for each additional unit in a multi-unit purchase; $34,000 for an add-on conversion; 15% discount for veterans via VetFran — 2025 FDD Item 5
Initial investment — low end: $190,501 — 2025 FDD Item 7
Initial investment — high end: $632,193 — 2025 FDD Item 7
Royalty: 7% of gross revenues per month — 2025 FDD Item 6
Ad / brand fund: 2% of gross revenues per month to the brand fund, plus a technology fee up to $250/month and a local marketing minimum of $1,000/month — 2025 FDD Item 6. NOTE: a 2024 FDD summary (Vetted Biz) reported the marketing fee at 1%, and Entrepreneur's 2026 Franchise 500 listing shows an ad royalty range of 1%–2%; confirm the current rate in the FDD you receive.

Liquid capital required: $150,000 (2025 FDD financial requirements per 1851franchise; the same $150,000 minimum liquidity is stated on the brand's own franchise-development site and in Entrepreneur's 2026 Franchise 500 listing)
Net worth required: $500,000 (2025 FDD financial requirements per 1851franchise). Entrepreneur's 2026 Franchise 500 listing states $400,000 — the two vintages disagree; verify against the FDD you are issued.
Term length: 10 years, renewable — Entrepreneur 2026 Franchise 500 directory listing. Not confirmed against a primary FDD Item 17 source.
Multi-unit commitment: No minimum multi-unit commitment is disclosed in any source read. Multi-unit purchases are incentivized rather than required: each additional unit is $39,000 instead of $49,000 (2025 FDD Item 5). 324 locations had been sold against 208 open as of 2025-12-31 (brand press release, 2026-02-09), indicating a large pipeline of committed-but-unopened units.
Territory model: Exclusive territories are granted (Entrepreneur 2026 Franchise 500 directory listing; also reported by FranchisePayback from the 2025 FDD). How the territory boundary is drawn — radius, population, or ZIP set — was not disclosed in any source read.

Reported unit economics (FDD Item 19)

2025 FDD Item 19, average gross sales for franchised units open 12+ months: 2022 — $534,770 across 31 units; 2023 — $698,937 across 49 units; 2024 — $567,075 across 99 units, with a median of $539,234. The 2024 average is below 2023 as the unit base doubled, which is the single most decision-relevant number here. FranchisePayback's summary of the same 2025 FDD lists AUV as $539,000 and separately notes the franchisor marks a field 'Undisclosed', so treat the per-year table above as the authoritative reading and confirm against the issued FDD.

Reported from public sources — named inline where the research records them — not verified against the primary FDD and not advice. Verify Items 5–7, 12 and 19 of the current FDD before relying on any figure. Primary economics source ↗

Research sources for this page (17)

Franchise system

Prime IV Hydration & Wellness

IV hydration and nutrient infusion clinics; the brand's own line is "Look Better, Feel Better, Perform Better with Prime IV" (primeivhydration.com/about, retrieved 2026-08-10).

IV hydration and nutrient infusion (custom drips)Micronutrient / vitamin injections (B-12, Lipo-Lean)NAD+ infusions and injectionsNiagen (NAD+ precursor)Buccal nutrient stripsMedical-grade oxygen

112

verified locations (Praxium)

208

units claimed by brand (2025)

states

2017

founded

Signature offer

What makes Prime IV Hydration & Wellness different

Footprint

Two counts, side by side

The brand's own unit count and Praxium's verified-location count measure different things and are shown unreconciled.

112

verified locations

Praxium’s own count — locations we linked to this brand, one by one.

208

units claimed by the brand · as of 2025

Franchise availability Open — per the brand's own materials. A status, not an endorsement.

For members

What Prime IV Hydration & Wellness sells members

On the record

Prime IV Hydration & Wellness in the news

2026-02-09
Reported 2025 results: 53 locations opened, closing the year at 208 operating locations; 35 new franchise agreements awarded bringing total sold to 324 across 42 states and DC; systemwide revenue up 41% year over year to $100M+; top-performing location at $3.2M annual revenue. Launched buccal nutrient strips, BHRT, and Niagen; entered Connecticut and Nebraska.
Source: Prime IV Hydration & Wellness press release, "Caps Off a Landmark Year of Growth and Innovation in 2025" (
2025-12-17
Received senior secured financing from Lafayette Square through its SSBIC investment vehicle to support franchise-system expansion; Boxwood Partners served as exclusive financial advisor. Amount undisclosed. Prime IV cited at 189 active locations across 40 states and described as a woman-owned business founded by Amy Neary. This is debt financing, not a sale — no change of control.
Source: Lafayette Square press release (
2026-02-09
Ranked #234 on Entrepreneur's Franchise 500 for 2026 and #1 in the IV Therapy category for the third consecutive year; ranked #597 on the 2025 Inc. 5000; Franchise Business Review #6 Top 50 Midsize Franchises and #2 in Health & Personal Services.
Source: Prime IV Hydration & Wellness press release (third-party rankings as reported by the brand); Entrepreneur Franchise 500 directory listing (
2026
FDD filings on record for 2020 through 2026, confirming continuous franchise registration since 2020 and an active current-year filing.
Source: FranchiseGenius FDD index (

In the directory

Prime IV Hydration & Wellness locations Praxium lists

112 of the 112 verified locations resolve to a listed US studio page across 27 states — the two counts differ because directory listings apply their own gates.

Prime IV Hydration & Wellness - Orlando - Dr. Phillips

Orlando, FL

5.0· 481 reviews

Prime IV Hydration Offers the Best IV Therapy in Florida - Infusions Formulated to Help You Look, Feel, & Perform Better.

IV & hydration

Website ↗

Prime IV Hydration & Wellness - Brentwood

Brentwood, TN

5.0· 274 reviews

Prime IV Hydration & Wellness in Brentwood specializes in intravenous vitamin infusions designed to enhance hydration, athletic performance, and anti-aging, with additional services including whole-body cryotherapy and medical-grade oxygen therapy.

IV & hydrationCryotherapyOxygen Bar

Website ↗

Prime IV Hydration & Wellness - Monument

Colorado Springs, CO

5.0· 266 reviews

Prime IV Hydration & Wellness offers premium IV therapy treatments including hydration infusions, NAD+ therapy, and vitamin injections designed to enhance your look, feel, and athletic performance.

IV & hydration

Website ↗

Prime IV Hydration & Wellness - Frisco

Frisco, TX

5.0· 237 reviews

Premier IV hydration clinic in Frisco, TX offering IV vitamin therapy for anti-aging, fatigue, immune system boost, and athletic performance recovery.

IV & hydration

Website ↗

Prime IV Hydration & Wellness - Meridian

Meridian, ID

5.0· 208 reviews

Prime IV Hydration & Wellness offers customized IV vitamin therapy infusions designed to optimize health and performance through direct bloodstream nutrient delivery.

IV & hydration

Website ↗

Prime IV Hydration & Wellness - Wall

Wall, NJ

5.0· 182 reviews

Premier IV hydration therapy clinic offering customized vitamin infusions for anti-aging, immune support, athletic recovery, and wellness.

IV & hydration

Website ↗

ALAZCOCTFLGAIDILKYMAMONCNDNENHNJNVOHRISCSDTNTXUTVAWAWIThe brand’s own location list ↗

Brand details

Company

Founded: 2017
Headquarters: Colorado Springs, CO
Founders: Amy Neary
Parent company: None identified. Private, founder-led franchisor; described as a woman-owned business founded by Amy Neary in the Lafayette Square financing announcement (2025-12-17). No parent holding company or PE sponsor found.

System

Ownership model: Franchise system

Franchisee support, as published

Site selection
Lease negotiation
Classroom training — 24.5 hours (Entrepreneur 2026 Franchise 500 listing)
On-the-job training — 16 hours (Entrepreneur 2026 Franchise 500 listing)
Field operations support
Proprietary software and franchisee intranet
Co-op advertising
Social media, SEO, and website development
Loyalty program
Ongoing operations team access — the brand's franchise site states "You get a team of experts available for training and help"

Visit Prime IV Hydration & Wellness ↗The brand’s franchise page ↗

The dossier

What it costs to open a Prime IV Hydration & Wellness

Terms tied to the 2025 disclosure cycle. Citations stay inline wherever the research recorded one.

Franchise fee: $49,000 per location; $39,000 for each additional unit in a multi-unit purchase; $34,000 for an add-on conversion; 15% discount for veterans via VetFran — 2025 FDD Item 5
Initial investment — low end: $190,501 — 2025 FDD Item 7
Initial investment — high end: $632,193 — 2025 FDD Item 7
Royalty: 7% of gross revenues per month — 2025 FDD Item 6
Ad / brand fund: 2% of gross revenues per month to the brand fund, plus a technology fee up to $250/month and a local marketing minimum of $1,000/month — 2025 FDD Item 6. NOTE: a 2024 FDD summary (Vetted Biz) reported the marketing fee at 1%, and Entrepreneur's 2026 Franchise 500 listing shows an ad royalty range of 1%–2%; confirm the current rate in the FDD you receive.

Liquid capital required: $150,000 (2025 FDD financial requirements per 1851franchise; the same $150,000 minimum liquidity is stated on the brand's own franchise-development site and in Entrepreneur's 2026 Franchise 500 listing)
Net worth required: $500,000 (2025 FDD financial requirements per 1851franchise). Entrepreneur's 2026 Franchise 500 listing states $400,000 — the two vintages disagree; verify against the FDD you are issued.
Term length: 10 years, renewable — Entrepreneur 2026 Franchise 500 directory listing. Not confirmed against a primary FDD Item 17 source.
Multi-unit commitment: No minimum multi-unit commitment is disclosed in any source read. Multi-unit purchases are incentivized rather than required: each additional unit is $39,000 instead of $49,000 (2025 FDD Item 5). 324 locations had been sold against 208 open as of 2025-12-31 (brand press release, 2026-02-09), indicating a large pipeline of committed-but-unopened units.
Territory model: Exclusive territories are granted (Entrepreneur 2026 Franchise 500 directory listing; also reported by FranchisePayback from the 2025 FDD). How the territory boundary is drawn — radius, population, or ZIP set — was not disclosed in any source read.

Reported unit economics (FDD Item 19)

Research sources for this page (17)