Cardiorespiratory fitness measured by exercise testing is a graded, independent predictor of long-term all-cause mortality, which is why obtaining even an estimate of it is worthwhile.
How strong the finding is
Large retrospective cohort plus an AHA scientific statement supporting routine assessment. Strong for the metric, not for any particular estimation shortcut.
What complicates this
These outcomes rest on measured or performance-derived fitness, not on submaximal estimates, so the prognostic strength does not transfer intact to an estimated value.
Sources (2)
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign (AHA Scientific Statement) — Circulation 134(24):e653-e699 · 2016-01-01
Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing — JAMA Network Open (2018) · 2018-01-01