In a randomized trial of massage-based decongestive therapy for breast-cancer-related lymphedema, the therapy did not produce a
In a randomized trial of massage-based decongestive therapy for breast-cancer-related lymphedema, the therapy did not produce a statistically significant reduction in percent excess arm volume compared with a more conservative approach, though it did produce a larger absolute volume loss on one secondary measure.
How it may work
Massage-based decongestive therapy aims to mobilize lymph fluid manually; the trial tested whether this manual component outperformed a simpler conservative management approach using compression garments alone.
What complicates this
Mean excess-arm-volume reduction was 29.0% with decongestive therapy versus 22.6% with conservative care, a 6.4% difference that was not statistically significant (95% CI -6.8% to 20.5%, P=.34). Absolute volume loss favored the therapy group (250 mL vs 143 mL, difference 107 mL, P=.03), but that was the only significant outcome, and the authors themselves state they were unable to demonstrate a significant improvement over the conservative approach.
Safety notes
No safety signal was raised; the finding concerns uncertain added benefit, not harm. Quality of life and arm function did not differ between groups.
Source
Randomized trial of decongestive lymphatic therapy for the treatment of lymphedema in women with breast cancer — Journal of Clinical Oncology · 2013





