LC6: Cryo neck wrap reduces migraine pain short-term — Grade B Moderate
A carotid/neck cold wrap reduces migraine pain ~31.8% at 30 min vs. a 31.5% increase in control; meta-analysis confirms short-term VAS reduction (SMD -3.21 at 30 min). Long-term benefit is marginal (CI crosses null).
How strong the finding is
Sprouse-Blum et al. PMID 23901394 (RCT n=55 crossover); Hsu et al. J Clinical Nursing 2023, 6 studies (DOI 10.1111/jocn.16368). Source: PMID 23901394. Dossier claim id LC6. Specific wrap device, not general cryo gun.
How it may work
Cooling of carotid blood and local vasoconstriction reduce migraine pain transmission.
What complicates this
Short-term only; long-term benefit not established (SMD -0.44, CI crosses null).
Source
Sprouse-Blum AS et al. — RCT: Targeted Neck Cooling in the Treatment of the Migraine Patient (Hawaii J Med Public Health, 2013) — PubMed / Hawaii Journal of Medicine & Public Health · 2013-07-01T00:00:00.000Z


















