In eight small and methodologically mixed studies of musculoskeletal injury, manual lymphatic drainage was associated with reduced swelling and pain and improved range of motion, but only half the studies rated strong on quality assessment.
How strong the finding is
A 2021 systematic review in Complementary Therapies in Clinical Practice included eight articles and reported reduced edema and pain along with better range of motion, quality of life, and patient satisfaction. Half the included studies achieved a strong quality assessment, and the authors called for further investigation before extending the conclusion to other injury types.
What complicates this
A 2024 meta-analysis of seven randomized trials after total knee replacement found no benefit for swelling, range of motion, or pain, so the positive injury-population signal does not generalize to post-arthroplasty rehabilitation.
Source
Manual lymphatic drainage for musculoskeletal injuries: systematic review — Provencher AM, Giguère-Lemieux É, Croteau É, Ruchat SM, Corbin-Berrigan LA · 2021



